According to The Aviation Herald, the pilots of Ethiopian Airlines flight #ET343 from Khartoum to Addis Ababa fell alseep in flight.
On August 15,2022, the Boeing Boeing 737-800 (reg ET-AOB) was at 37,000 ft at FL370 when it was supposed to start the descent to Addis Ababa Bole Airport.
The Air Traffic Control tried to contact the crew several times without success. When the autopilot disocnnected, the alarm woke up the pilots who reacted and finally landed the plane on runway 25L about 25 minutes later.
In this case, it looks the flight management system was set up for an approach to the airport… without descending. The consequences could have been well worse if it was not the case.